Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P00688 (Created: 1986-07-21 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

AMYP_MOUSE

Protein Name

Pancreatic alpha-amylase

Gene

Amy2

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

508

Protein Mass [Da]

57417

Features

TypeDescriptionStatusStartEnd
signal peptide         1   15
chain   Pancreatic alpha-amylase      16   508
disulfide bond      by similarity   43   101
disulfide bond      by similarity   85   130
disulfide bond      by similarity   156   172
disulfide bond      by similarity   390   396
disulfide bond      by similarity   462   474
modified residue   Pyrrolidone carboxylic acid      16   16
sequence variant   (in A1, B(A), B(C))      0   0
sequence variant   (in A1, B(A), B(C); requires 2 nucleotide substitutions)      0   0
sequence variant   (in A1, B(C))      0   0
sequence variant   (in B(A))      0   0
sequence variant   (in A1, B(C))      0   0
sequence variant   (in A1, B(C))      0   0
sequence variant   (in A1, B(A), B(C))      0   0
sequence variant   (in B(A))      0   0
sequence variant   (in B1)      0   0
sequence variant   (in AMY-2.2Y)      0   0
sequence variant   (in A1, B(C), AMY-2.2Y)      0   0
sequence variant   (in B(C))      0   0
active site   Nucleophile   by similarity   209   209
active site   Proton donor   by similarity   245   245
active site      by similarity   312   312
metal ion-binding site   Calcium   by similarity   115   115
metal ion-binding site   Calcium; via carbonyl oxygen   by similarity   170   170
metal ion-binding site   Calcium   by similarity   179   179
metal ion-binding site   Calcium; via carbonyl oxygen   by similarity   213   213
binding site   Chloride   by similarity   207   207
binding site   Chloride   by similarity   310   310
binding site   Chloride   by similarity   349   349

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKFVLLLSLIGFCWA

Sequence

MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPK
GFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTR
CNNVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWD
FNDNKCNGEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLID
IGVAGFRLDAAKHMWPRDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLG
GEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVP
SDRALVFVDNHDNQRGHGAGGSSILTFWDARMYKMAVGFMLAHPYGFTRV
MSSYRWNRNFQNGKDQNDWIGPPNNNGVTKEVTINADTTCGNDWVCEHRW
RQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSA
TLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFI
AIHADSKL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website