Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

A2AJA7 (Created: 2007-05-15 Updated: 2008-11-04)

UniProtKB/Swiss-Prot Entry Name

AEGP_MOUSE

Protein Name

Apical endosomal glycoprotein

Gene

Mamdc4

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

1228

Protein Mass [Da]

134830

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   21
chain   Apical endosomal glycoprotein      22   1228
disulfide bond      by similarity   230   242
disulfide bond      by similarity   237   255
disulfide bond      by similarity   249   266
disulfide bond      by similarity   458   469
disulfide bond      by similarity   465   482
disulfide bond      by similarity   476   491
transmembrane region      potential   1160   1180
topological domain   Extracellular   potential   23   1159
topological domain   Cytoplasmic   potential   1181   1228
domain   LDL-receptor class A 1; truncated      28   49
domain   MAM 1      65   223
domain   LDL-receptor class A 2      229   267
domain   MAM 2      270   426
domain   LDL-receptor class A 3      457   492
domain   MAM 3      492   649
domain   MAM 4      659   815
domain   MAM 5      817   975
domain   MAM 6      977   1144
modified residue   Phosphothreonine   by similarity   198   198
modified residue   Phosphothreonine   by similarity   206   206
glycosylation site   N-linked (GlcNAc...)   potential   204   204
glycosylation site   N-linked (GlcNAc...)   potential   290   290
glycosylation site   N-linked (GlcNAc...)   potential   340   340
glycosylation site   N-linked (GlcNAc...)   potential   641   641
glycosylation site   N-linked (GlcNAc...)   potential   841   841
splice variant   (in isoform 2)      578   656

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MCLPSHLLSTWVLFMAAQSLG

Sequence

MCLPSHLLSTWVLFMAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDET
QCGFHGASTIPSTSFTCNFEQDSCGWQDISTSGYRWLRDRAGAVLHGPGP
HSDHTHGTDLGWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIA
SRDVAELRLDLTHGVETLTLWQTSGPWGPGWQELAVNTGRIQGDFKVTFS
ATRNATHRGAVALDDVEFRDCGLPIPQARCPLGHHHCQNKACVEPHQLCD
GEDNCGDRSDEDPLICSHHMATDFETGLGPWNQLEGWTRNHSAGSMVSPA
WPHRDHSRNSAYGFFLISVAKPGTTAVLYSPEFQGSVSNNCSFTFYYYLH
GSEASHFQLFLQAQGLNTPQVPVLLRSRHGELGTAWVRDRVDIQSAHPFR
ILLAGETGPGGVVGLDDLIMSSHCMLVPAMSTLQSSLSGPVPLALYPQTS
IKLPQQTCEPGHLSCGDLCVPPEQLCDFQKHCAEGEDEHKCGTTDFESAS
AGGWEDISVGKLQWQWVEAQEKSKPAGDANRDAPGHFLSLQKAWGQLRSE
ARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVENGFRELLWQAPGG
GSGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRDCNPM
VTTESDQELSCNFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQGFFM
FLDPTDPPARGQGALLLTRPQVPVVPKECLSFWYRLYGPQIGTLCLAMRR
EREEDILLWSRSGTHGNRWHQAWVTLHHQPEASTKYQLLFEGLRNGYHGT
MALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTHQSNASGLASWGP
WIDHTTGTAQGHYMVVDTSPNVLPKGHVAALTSEEHQPLSQPACLTFWYH
MSVPNPGTLRVHVEESTRRQELSISAHGRSAWRLGSVNVQAEQAWKVVFE
AVAAGVEYSYMALDDISLQDGPCPQPGSCDFETGLCGWSHLPWPSLGGYS
WDWSSGATPSRYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPL
PATTVSCLRFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWL
QVQIELSNSEEFQIVFEATLGGQPALGPIAIDDVQYLAGQQCKQPSPSQG
EVAAPVSVPVAVGGALLFFMFLVLMGLGGWHWLQKQHCPGQRSTDAAASG
FANILFNADHVTLPESITSNPQSPPDLA

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website