Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q8SPU7 (Created: 2006-06-27 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ACHA5_BOVIN

Protein Name

Neuronal acetylcholine receptor subunit alpha-5

Gene

CHRNA5

Organism Scientific

Bos taurus

Organism Common

Bovine

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Laurasiatheria
                  Cetartiodactyla
                    Ruminantia
                      Pecora
                        Bovidae
                          Bovinae
                            Bos

Protein Length [aa]

475

Protein Mass [Da]

54260

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   29
chain   Neuronal acetylcholine receptor subunit alpha-5      30   475
disulfide bond      by similarity   177   191
disulfide bond   Associated with receptor activation   by similarity   241   242
transmembrane region      potential   262   282
transmembrane region      potential   289   309
transmembrane region      potential   324   344
transmembrane region      potential   438   458
topological domain   Extracellular   by similarity   30   261
topological domain   Cytoplasmic   by similarity   345   437
topological domain   Extracellular   by similarity   459   475
glycosylation site   N-linked (GlcNAc...)   potential   190   190
glycosylation site   N-linked (GlcNAc...)   potential   236   236

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MAAPGWGRWVLGLGPLLLQVFLPFQLVAG

Sequence

MAAPGWGRWVLGLGPLLLQVFLPFQLVAGRWGPEGAGGGVRRGLAEPSVV
AKHEDSLFKDLFQDYERWVRPVEHLNDRIKIKFGLAISQLVDVDEKNQLM
TTNVWLKQEWIDVKLRWNPDDYGGIKLIRVPSDSLWTPDIVLFDNADGRF
EGASTKTVVRYDGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTY
DGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYITYS
FVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLT
VFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSS
THDAMAPWVRKIFLHKLPKLLCMRSHVDRYFSQKEEARSSRGPRSSRNAL
EAALDSVRYITRHVMKETDVREVVEDWKFIAQVLDRMFLWTFLLVSVVGS
LGLFVPVIYKWANIIVPIHIGNENK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website