Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9GLN7 (Created: 2005-08-30 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

ACE_PANTR

Protein Name

Angiotensin-converting enzyme, somatic isoform

Gene

ACE

Organism Scientific

Pan troglodytes

Organism Common

Chimpanzee

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Pan

Protein Length [aa]

1304

Protein Mass [Da]

149370

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   27
chain   Angiotensin-converting enzyme, somatic isoform      28   1304
chain   Angiotensin-converting enzyme, somatic isoform, soluble form      28   1230
transmembrane region      potential   1258   1274
topological domain   Extracellular   potential   28   1257
topological domain   Cytoplasmic   potential   1275   1304
region of interest   Peptidase M2 1      28   628
region of interest   Peptidase M2 2      629   1230
modified residue   Phosphoserine   by similarity   1297   1297
glycosylation site   N-linked (GlcNAc...)   potential   36   36
glycosylation site   N-linked (GlcNAc...)   potential   72   72
glycosylation site   N-linked (GlcNAc...)   potential   109   109
glycosylation site   N-linked (GlcNAc...)   potential   144   144
glycosylation site   N-linked (GlcNAc...)   potential   316   316
glycosylation site   N-linked (GlcNAc...)   potential   440   440
glycosylation site   N-linked (GlcNAc...)   potential   712   712
active site   1   by similarity   389   389
active site   2   by similarity   987   987
propeptide   Removed in secreted form   by similarity   1231   1304
metal ion-binding site   Zinc 1; catalytic   by similarity   388   388
metal ion-binding site   Zinc 1; catalytic   by similarity   392   392
metal ion-binding site   Zinc 2; catalytic   by similarity   986   986
metal ion-binding site   Zinc 2; catalytic   by similarity   990   990
metal ion-binding site   Zinc 2; catalytic   by similarity   1014   1014
binding site   Chloride 1   by similarity   789   789
binding site   Chloride 2   by similarity   827   827
binding site   Chloride 1   by similarity   1088   1088
binding site   Chloride 1   by similarity   1092   1092
binding site   Chloride 2   by similarity   1125   1125

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MGAASGRRGPGLLLPLLLLLPPQPALA

Sequence

MGAASGRRGPGLLLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQS
YNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAK
ELYEPVWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYS
TAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKP
LYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYL
NLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPD
KPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPA
DGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYK
DLPVSLRGGANPGFHEAIGDVLALSVSTPAHLHKIGLLDNVTNDTESDIN
YLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPNSRYNFDWWYLRTKYQGI
CPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEG
PLHQCDIYQSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKY
FQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKF
VEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGT
QARRFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYS
VATVCHTNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFY
PKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNL
HAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAP
SMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDG
REVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDL
PVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFL
MKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCP
PVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPL
HKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFK
PLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDA
QQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFDSEVE
LRHS

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website