Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

112

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P25774 (Created: 1992-05-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

CATS_HUMAN

Protein Name

Cathepsin S

Gene

CTSS

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

331

Protein Mass [Da]

37496

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   16
chain   Cathepsin S      115   331
disulfide bond         126   224
disulfide bond         136   180
disulfide bond         170   213
disulfide bond         272   320
glycosylation site   N-linked (GlcNAc...)   potential   104   104
sequence variant   (in dbSNP:rs2230061)      0   0
sequence variant   (in dbSNP:rs1059604)      0   0
strand         198   200
strand         220   222
strand         225   229
strand         248   252
strand         264   267
strand         278   288
strand         291   297
strand         309   313
strand         315   318
strand         327   330
helix         121   124
helix         139   156
helix         164   170
helix         173   175
helix         185   195
helix         217   219
helix         235   244
helix         257   261
helix         319   321
active site      by similarity   139   139
active site      by similarity   278   278
active site      by similarity   298   298
propeptide   Activation peptide      17   114
turn         201   203
turn         322   324

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKRLVCVLLVCSSAVA

Sequence

MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL
IWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQ
WQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEA
QLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDS
DASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSV
GVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website